diff --git a/src/slic3r/GUI/DeviceManager.cpp b/src/slic3r/GUI/DeviceManager.cpp
index 5ff3f5436..e2750dd33 100644
--- a/src/slic3r/GUI/DeviceManager.cpp
+++ b/src/slic3r/GUI/DeviceManager.cpp
@@ -903,6 +903,20 @@ bool MachineObject::is_support_amx_ext_mix_mapping() {
     return true;
 }
 
+/* the API is developing by AP, not completed now*/
+bool MachineObject::is_ams_on_settingup() const
+{
+    for (const auto& ext : m_extder_data.extders)
+    {
+        if (ext.ams_stat != 0)
+        {
+            return true;
+        }
+    }
+
+    return false;
+}
+
 static float calc_color_distance(wxColour c1, wxColour c2)
 {
     float lab[2][3];
@@ -4338,6 +4352,8 @@ int MachineObject::parse_json(std::string payload, bool key_field_only)
 
                                     /*AMS without initialization*/
                                     if (nozzle_id == 0xE) {
+                                        ams_id_set.erase(ams_id);
+                                        amsList.erase(ams_id);
                                         continue;
                                     }
 
diff --git a/src/slic3r/GUI/DeviceManager.hpp b/src/slic3r/GUI/DeviceManager.hpp
index ec7b2d8d6..572b97a34 100644
--- a/src/slic3r/GUI/DeviceManager.hpp
+++ b/src/slic3r/GUI/DeviceManager.hpp
@@ -695,6 +695,8 @@ public:
     bool    is_ams_need_update;
 
     inline bool is_ams_unload() { return m_tray_tar.compare("255") == 0; }
+    [[nodiscard]] bool is_ams_on_settingup() const;
+
     Ams*     get_curr_Ams();
     AmsTray* get_curr_tray();
     AmsTray *get_ams_tray(std::string ams_id, std::string tray_id);
diff --git a/src/slic3r/GUI/SelectMachine.cpp b/src/slic3r/GUI/SelectMachine.cpp
index 3c9ec35a1..e711b0a9e 100644
--- a/src/slic3r/GUI/SelectMachine.cpp
+++ b/src/slic3r/GUI/SelectMachine.cpp
@@ -1737,6 +1737,10 @@ void SelectMachineDialog::show_status(PrintDialogStatus status, std::vector<wxSt
         update_print_status_msg(msg_text, true, true);
         Enable_Send_Button(false);
         Enable_Refresh_Button(true);
+    } else if (status == PrintDialogStatus::PrintStatusAmsOnSettingup) {
+        update_print_status_msg(_L("AMS is setting up. Please try again later."), false, false);
+        Enable_Send_Button(false);
+        Enable_Refresh_Button(true);
     } else if (status == PrintDialogStatus::PrintStatusDisableAms) {
         update_print_status_msg(wxEmptyString, false, false);
         Enable_Send_Button(true);
@@ -1750,7 +1754,7 @@ void SelectMachineDialog::show_status(PrintDialogStatus status, std::vector<wxSt
         update_print_status_msg(msg_text, true, false);
         Enable_Send_Button(false);
         Enable_Refresh_Button(true);
-    } else if (status == PrintDialogStatus::PrintStatusAmsMappingSuccess){
+    }  else if (status == PrintDialogStatus::PrintStatusAmsMappingSuccess){
         wxString msg_text = _L("Filaments to AMS slots mappings have been established. You can click a filament above to change its mapping AMS slot");
         update_print_status_msg(msg_text, false, false);
         Enable_Send_Button(true);
@@ -3362,6 +3366,12 @@ void SelectMachineDialog::update_show_status()
     }
 
     // check ams and vt_slot mix use status
+    if (obj_->is_ams_on_settingup())
+    {
+        show_status(PrintDialogStatus::PrintStatusAmsOnSettingup);
+        return;
+    }
+
     struct ExtruderStatus
     {
         bool has_ams{false};
diff --git a/src/slic3r/GUI/SelectMachine.hpp b/src/slic3r/GUI/SelectMachine.hpp
index 72f1e15e9..eb108e6b7 100644
--- a/src/slic3r/GUI/SelectMachine.hpp
+++ b/src/slic3r/GUI/SelectMachine.hpp
@@ -73,6 +73,7 @@ enum PrintDialogStatus {
     PrintStatusInSystemPrinting,
     PrintStatusInPrinting,
     PrintStatusDisableAms,
+    PrintStatusAmsOnSettingup,
     PrintStatusAmsMappingSuccess,
     PrintStatusAmsMappingInvalid,
     PrintStatusAmsMappingU0Invalid,