diff --git a/src/libslic3r/Config.hpp b/src/libslic3r/Config.hpp
index 937213f17..fb77e85e5 100644
--- a/src/libslic3r/Config.hpp
+++ b/src/libslic3r/Config.hpp
@@ -355,9 +355,12 @@ public:
     // This function is useful to split values from multiple extrder / filament settings into separate configurations.
     virtual void set_at(const ConfigOption *rhs, size_t i, size_t j) = 0;
     //BBS
+    virtual void set_at_to_nil(size_t i) = 0;
     virtual void append(const ConfigOption *rhs) = 0;
     virtual void set(const ConfigOption* rhs, size_t start, size_t len) = 0;
-    virtual void set_with_keep(const ConfigOptionVectorBase* rhs, std::vector<int>& keep_index, int stride) = 0;
+    virtual void set_with_restore(const ConfigOptionVectorBase* rhs, std::vector<int>& restore_index, int stride) = 0;
+    virtual void set_only_diff(const ConfigOptionVectorBase* rhs, std::vector<int>& diff_index, int stride) = 0;
+    virtual void set_with_nil(const ConfigOptionVectorBase* rhs, const ConfigOptionVectorBase* inherits, int stride) = 0;
     // Resize the vector of values, copy the newly added values from opt_default if provided.
     virtual void resize(size_t n, const ConfigOption *opt_default = nullptr) = 0;
     // Clear the values vector.
@@ -446,6 +449,8 @@ public:
     }
 
     //BBS
+    virtual void set_at_to_nil(size_t i) override {}
+
     void append(const ConfigOption *rhs) override
     {
         if (rhs->type() == this->type()) {
@@ -480,7 +485,10 @@ public:
             throw ConfigurationError("ConfigOptionVector::set_with(): Assigning an incompatible type");
     }
 
-    virtual void set_with_keep(const ConfigOptionVectorBase* rhs, std::vector<int>& keep_index, int stride) override
+    //set a item related with extruder variants when loading config from 3mf, restore the non change values to system config
+    //rhs: item from systemconfig(inherits)
+    //keep_index: which index in this vector need to be restored
+    virtual void set_with_restore(const ConfigOptionVectorBase* rhs, std::vector<int>& restore_index, int stride) override
     {
         if (rhs->type() == this->type()) {
             //backup original ones
@@ -489,13 +497,13 @@ public:
             auto other = static_cast<const ConfigOptionVector<T>*>(rhs);
             this->values = other->values;
 
-            if (other->values.size() != keep_index.size())
-                throw ConfigurationError("ConfigOptionVector::set_with_keep(): Assigning from an vector with invalid keep_index size");
+            if (other->values.size() != (restore_index.size()*stride))
+                throw ConfigurationError("ConfigOptionVector::set_with_restore(): Assigning from an vector with invalid restore_index size");
 
-            for (size_t i = 0; i < keep_index.size(); i++) {
-                if (keep_index[i] != -1) {
+            for (size_t i = 0; i < restore_index.size(); i++) {
+                if (restore_index[i] != -1) {
                     for (size_t j = 0; j < stride; j++)
-                        this->values[i * stride +j] = backup_values[keep_index[i] * stride +j];
+                        this->values[i * stride +j] = backup_values[restore_index[i] * stride +j];
                 }
             }
         }
@@ -503,6 +511,67 @@ public:
             throw ConfigurationError("ConfigOptionVector::set_with_keep(): Assigning an incompatible type");
     }
 
+    //set a item related with extruder variants when loading user config, only set the different value of some extruder
+    //rhs: item from user config
+    //diff_index: which index in this vector need to be set
+    virtual void set_only_diff(const ConfigOptionVectorBase* rhs, std::vector<int>& diff_index, int stride) override
+    {
+        if (rhs->type() == this->type()) {
+            // Assign the first value of the rhs vector.
+            auto other = static_cast<const ConfigOptionVector<T>*>(rhs);
+
+            if (this->values.size() != (diff_index.size()*stride))
+                throw ConfigurationError("ConfigOptionVector::set_only_diff(): Assigning from an vector with invalid diff_index size");
+
+            for (size_t i = 0; i < diff_index.size(); i++) {
+                if (diff_index[i] != -1) {
+                    for (size_t j = 0; j < stride; j++)
+                    {
+                        if (!other->is_nil(diff_index[i]))
+                            this->values[i * stride +j] = other->values[diff_index[i] * stride +j];
+                    }
+                }
+            }
+        }
+        else
+            throw ConfigurationError("ConfigOptionVector::set_only_diff(): Assigning an incompatible type");
+    }
+
+    //set a item related with extruder variants when saving user config, set the non-diff value of some extruder to nill
+    //this item has different value with inherit config
+    //rhs: item from userconfig
+    //inherits: item from inherit config
+    virtual void set_with_nil(const ConfigOptionVectorBase* rhs, const ConfigOptionVectorBase* inherits, int stride) override
+    {
+        if ((rhs->type() == this->type()) && (inherits->type() == this->type())) {
+            auto rhs_opt = static_cast<const ConfigOptionVector<T>*>(rhs);
+            auto inherits_opt = static_cast<const ConfigOptionVector<T>*>(inherits);
+
+            if (inherits->size() != rhs->size())
+                throw ConfigurationError("ConfigOptionVector::set_with_nil(): rhs size different with inherits size");
+
+            for (size_t i = 0; i < inherits_opt->size(); i= i+stride) {
+                bool set_nil = true;
+                for (size_t j = 0; j < stride; j++) {
+                    if (inherits_opt->values[i +j] != rhs_opt->values[i +j]) {
+                        set_nil = false;
+                        break;
+                    }
+                }
+
+                for (size_t j = 0; j < stride; j++) {
+                    if (set_nil) {
+                        this->set_at_to_nil(i +j);
+                    }
+                    else
+                        this->values[i +j] = rhs_opt->values[i +j];
+                }
+            }
+        }
+        else
+            throw ConfigurationError("ConfigOptionVector::set_with_nil(): Assigning an incompatible type");
+    }
+
     const T& get_at(size_t i) const
     {
         assert(! this->values.empty());
@@ -701,6 +770,11 @@ public:
     // A scalar is nil, or all values of a vector are nil.
     bool 					is_nil() const override { for (auto v : this->values) if (! std::isnan(v)) return false; return true; }
     bool 					is_nil(size_t idx) const override { return std::isnan(this->values[idx]); }
+    virtual void set_at_to_nil(size_t i) override
+    {
+        assert(nullable() && (i < this->values.size()));
+        this->values[i] = nil_value();
+    }
 
     std::string serialize() const override
     {
@@ -862,6 +936,11 @@ public:
     // A scalar is nil, or all values of a vector are nil.
     bool 					is_nil() const override { for (auto v : this->values) if (v != nil_value()) return false; return true; }
     bool 					is_nil(size_t idx) const override { return this->values[idx] == nil_value(); }
+    virtual void set_at_to_nil(size_t i) override
+    {
+        assert(nullable() && (i < this->values.size()));
+        this->values[i] = nil_value();
+    }
 
     std::string serialize() const override
     {
@@ -1186,6 +1265,11 @@ public:
     // A scalar is nil, or all values of a vector are nil.
     bool                    is_nil() const override { for (auto v : this->values) if (! std::isnan(v.value)) return false; return true; }
     bool                    is_nil(size_t idx) const override { return std::isnan(this->values[idx].value); }
+    virtual void set_at_to_nil(size_t i) override
+    {
+        assert(nullable() && (i < this->values.size()));
+        this->values[i] = nil_value();
+    }
 
     std::string serialize() const override
     {
@@ -1502,6 +1586,11 @@ public:
     // A scalar is nil, or all values of a vector are nil.
     bool 					is_nil() const override { for (auto v : this->values) if (v != nil_value()) return false; return true; }
     bool 					is_nil(size_t idx) const override { return this->values[idx] == nil_value(); }
+    virtual void set_at_to_nil(size_t i) override
+    {
+        assert(nullable() && (i < this->values.size()));
+        this->values[i] = nil_value();
+    }
 
     bool& get_at(size_t i) {
         assert(! this->values.empty());
@@ -2171,6 +2260,7 @@ public:
     // An UnknownOptionException is thrown in case some option keys are not defined by this->def(),
     // or this ConfigBase is of a StaticConfig type and it does not support some of the keys, and ignore_nonexistent is not set.
     void apply_only(const ConfigBase &other, const t_config_option_keys &keys, bool ignore_nonexistent = false);
+
     // Are the two configs equal? Ignoring options not present in both configs.
     //BBS: add skipped_keys logic
     bool equals(const ConfigBase &other, const std::set<std::string>* skipped_keys = nullptr) const;
diff --git a/src/libslic3r/Preset.cpp b/src/libslic3r/Preset.cpp
index 30662cdd0..ca3cc2c8f 100644
--- a/src/libslic3r/Preset.cpp
+++ b/src/libslic3r/Preset.cpp
@@ -523,11 +523,36 @@ bool Preset::save(DynamicPrintConfig* parent_config)
         DynamicPrintConfig temp_config;
         std::vector<std::string> dirty_options = config.diff(*parent_config);
 
+        std::string extruder_id_name, extruder_variant_name;
+        std::set<std::string> *key_set1 = nullptr, *key_set2 = nullptr;
+        Preset::get_extruder_names_and_keysets(type, extruder_id_name, extruder_variant_name, &key_set1, &key_set2);
+
+        if (!extruder_id_name.empty()) {
+            dirty_options.emplace_back(extruder_id_name);
+        }
+        if (!extruder_variant_name.empty()) {
+            dirty_options.emplace_back(extruder_variant_name);
+        }
+
         for (auto option: dirty_options)
         {
             ConfigOption *opt_src = config.option(option);
             ConfigOption *opt_dst = temp_config.option(option, true);
-            opt_dst->set(opt_src);
+            if (opt_dst->is_scalar() || !(opt_dst->nullable()))
+                opt_dst->set(opt_src);
+            else {
+                ConfigOptionVectorBase* opt_vec_src = static_cast<ConfigOptionVectorBase*>(opt_src);
+                ConfigOptionVectorBase* opt_vec_dst = static_cast<ConfigOptionVectorBase*>(opt_dst);
+                ConfigOptionVectorBase* opt_vec_inherit = static_cast<ConfigOptionVectorBase*>(parent_config->option(option));
+                if (key_set1->find(option) != key_set1->end()) {
+                    opt_vec_dst->set_with_nil(opt_vec_src, opt_vec_inherit, 1);
+                }
+                else if (key_set2->find(option) != key_set2->end()) {
+                    opt_vec_dst->set_with_nil(opt_vec_src, opt_vec_inherit, 2);
+                }
+                else
+                    opt_dst->set(opt_src);
+            }
         }
         temp_config.save_to_json(this->file, this->name, from_str, this->version.to_string(), this->custom_defined);
     } else if (!filament_id.empty() && inherits().empty()) {
@@ -709,6 +734,31 @@ std::string Preset::get_current_printer_type(PresetBundle *preset_bundle)
     return "";
 }
 
+void Preset::get_extruder_names_and_keysets(Type type, std::string& extruder_id_name, std::string& extruder_variant_name, std::set<std::string>** p_key_set1, std::set<std::string>** p_key_set2)
+{
+    if (type == Preset::TYPE_PRINT) {
+        extruder_id_name = "print_extruder_id";
+        extruder_variant_name = "print_extruder_variant";
+        *p_key_set1 = &print_options_with_variant;
+        *p_key_set2 = &empty_options;
+    }
+    else if (type == Preset::TYPE_PRINTER) {
+        extruder_id_name = "printer_extruder_id";
+        extruder_variant_name = "printer_extruder_variant";
+        *p_key_set1 = &printer_options_with_variant_1;
+        *p_key_set2 = &printer_options_with_variant_2;
+    }
+    else if (type == Preset::TYPE_FILAMENT) {
+        extruder_variant_name = "filament_extruder_variant";
+        *p_key_set1 = &filament_options_with_variant;
+        *p_key_set2 = &empty_options;
+    }
+    else {
+        *p_key_set1 = &empty_options;
+        *p_key_set2 = &empty_options;
+    }
+}
+
 bool Preset::has_lidar(PresetBundle *preset_bundle)
 {
     bool has_lidar = false;
@@ -1114,6 +1164,12 @@ void PresetCollection::load_presets(
     // Store the loaded presets into a new vector, otherwise the binary search for already existing presets would be broken.
     // (see the "Preset already present, not loading" message).
     std::deque<Preset> presets_loaded;
+
+    //BBS: get the extruder related info for this preset collection
+    std::string extruder_id_name, extruder_variant_name;
+    std::set<std::string> *key_set1 = nullptr, *key_set2 = nullptr;
+    Preset::get_extruder_names_and_keysets(m_type, extruder_id_name, extruder_variant_name, &key_set1, &key_set2);
+
     //BBS: change to json format
     for (auto &dir_entry : boost::filesystem::directory_iterator(dir))
     {
@@ -1192,6 +1248,7 @@ void PresetCollection::load_presets(
                     if (inherit_preset) {
                         preset.config = inherit_preset->config;
                         preset.filament_id = inherit_preset->filament_id;
+                        preset.config.update_diff_values_to_child_config(config, extruder_id_name, extruder_variant_name, *key_set1, *key_set2);
                     }
                     else {
                         // We support custom root preset now
@@ -1202,9 +1259,10 @@ void PresetCollection::load_presets(
                         }
                         // Find a default preset for the config. The PrintPresetCollection provides different default preset based on the "printer_technology" field.
                         preset.config = default_preset.config;
+                        preset.config.apply(std::move(config));
                     }
                     BOOST_LOG_TRIVIAL(info) << __FUNCTION__ << " load preset: " << name << " and filament_id: " << preset.filament_id << " and base_id: " << preset.base_id;
-                    preset.config.apply(std::move(config));
+
                     Preset::normalize(preset.config);
                     // Report configuration fields, which are misplaced into a wrong group.
                     std::string incorrect_keys = Preset::remove_invalid_keys(preset.config, default_preset.config);
@@ -1733,7 +1791,15 @@ bool PresetCollection::load_user_preset(std::string name, std::map<std::string,
             // Find a default preset for the config. The PrintPresetCollection provides different default preset based on the "printer_technology" field.
             new_config = default_preset.config;
         }
-        new_config.apply(std::move(cloud_config));
+        if (inherit_preset) {
+            std::string extruder_id_name, extruder_variant_name;
+            std::set<std::string> *key_set1 = nullptr, *key_set2 = nullptr;
+            Preset::get_extruder_names_and_keysets(m_type, extruder_id_name, extruder_variant_name, &key_set1, &key_set2);
+
+            new_config.update_diff_values_to_child_config(cloud_config, extruder_id_name, extruder_variant_name, *key_set1, *key_set2);
+        }
+        else
+            new_config.apply(std::move(cloud_config));
         Preset::normalize(new_config);
         // Report configuration fields, which are misplaced into a wrong group.
         std::string incorrect_keys = Preset::remove_invalid_keys(new_config, default_preset.config);
@@ -1910,24 +1976,9 @@ std::pair<Preset*, bool> PresetCollection::load_external_preset(
     }
 
     std::string extruder_id_name, extruder_variant_name;
-    std::set<std::string> *key_set1 = nullptr, *key_set2 = nullptr, empty_set;
-    if (m_type == Preset::TYPE_PRINT) {
-        extruder_id_name = "print_extruder_id";
-        extruder_variant_name = "print_extruder_variant";
-        key_set1 = &print_options_with_variant;
-        key_set2 = &empty_set;
-    }
-    else if (m_type == Preset::TYPE_PRINTER) {
-        extruder_id_name = "printer_extruder_id";
-        extruder_variant_name = "printer_extruder_variant";
-        key_set1 = &printer_options_with_variant_1;
-        key_set2 = &printer_options_with_variant_2;
-    }
-    else if (m_type == Preset::TYPE_FILAMENT) {
-        extruder_variant_name = "filament_extruder_variant";
-        key_set1 = &filament_options_with_variant;
-        key_set2 = &empty_set;
-    }
+    std::set<std::string> *key_set1 = nullptr, *key_set2 = nullptr;
+    Preset::get_extruder_names_and_keysets(m_type, extruder_id_name, extruder_variant_name, &key_set1, &key_set2);
+
     if (!inherits.empty() && (different_settings_list.size() > 0)) {
         auto iter = this->find_preset_internal(inherits);
         if (iter != m_presets.end() && iter->name == inherits) {
diff --git a/src/libslic3r/Preset.hpp b/src/libslic3r/Preset.hpp
index edac28dc9..6846e4898 100644
--- a/src/libslic3r/Preset.hpp
+++ b/src/libslic3r/Preset.hpp
@@ -243,7 +243,7 @@ public:
     std::string         base_id;         // base id of preset
     std::string         sync_info;       // enum: "delete", "create", "update", ""
     std::string         custom_defined;  // enum: "1", "0", ""
-    std::string         description;     // 
+    std::string         description;     //
     long long           updated_time{0};    //last updated time
     std::map<std::string, std::string> key_values;
 
@@ -315,6 +315,8 @@ public:
     std::string get_printer_type(PresetBundle *preset_bundle); // get edited preset type
     std::string get_current_printer_type(PresetBundle *preset_bundle); // get current preset type
 
+    static void get_extruder_names_and_keysets(Type type, std::string& extruder_id_name, std::string& extruder_variant_name, std::set<std::string>** p_key_set1, std::set<std::string>** p_key_set2);
+
     bool has_lidar(PresetBundle *preset_bundle);
     bool is_custom_defined();
 
diff --git a/src/libslic3r/PresetBundle.cpp b/src/libslic3r/PresetBundle.cpp
index 046c1d75a..a150851a7 100644
--- a/src/libslic3r/PresetBundle.cpp
+++ b/src/libslic3r/PresetBundle.cpp
@@ -2039,6 +2039,9 @@ DynamicPrintConfig PresetBundle::full_fff_config(bool apply_extruder, std::vecto
     if (filament_maps.empty()) {
         filament_maps.resize(num_filaments, 1);
     }
+    else {
+        assert(filament_maps.size() == num_filaments);
+    }
 
     auto* extruder_diameter = dynamic_cast<const ConfigOptionFloats*>(out.option("nozzle_diameter"));
     // Collect the "compatible_printers_condition" and "inherits" values over all presets (print, filaments, printers) into a single vector.
diff --git a/src/libslic3r/PrintConfig.cpp b/src/libslic3r/PrintConfig.cpp
index f710952f0..33daa9c60 100644
--- a/src/libslic3r/PrintConfig.cpp
+++ b/src/libslic3r/PrintConfig.cpp
@@ -5112,6 +5112,8 @@ std::set<std::string> printer_options_with_variant_2 = {
     "machine_max_jerk_e"
 };
 
+std::set<std::string> empty_options;
+
 DynamicPrintConfig DynamicPrintConfig::full_print_config()
 {
 	return DynamicPrintConfig((const PrintRegionConfig&)FullPrintConfig::defaults());
@@ -5819,7 +5821,7 @@ void DynamicPrintConfig::update_non_diff_values_to_base_config(DynamicPrintConfi
                     int stride = 1;
                     if (key_set2.find(opt) != key_set2.end())
                         stride = 2;
-                    opt_vec_src->set_with_keep(opt_vec_dest, variant_index, stride);
+                    opt_vec_src->set_with_restore(opt_vec_dest, variant_index, stride);
                 }
             }
         }
@@ -5827,6 +5829,81 @@ void DynamicPrintConfig::update_non_diff_values_to_base_config(DynamicPrintConfi
     return;
 }
 
+void DynamicPrintConfig::update_diff_values_to_child_config(DynamicPrintConfig& new_config, std::string extruder_id_name, std::string extruder_variant_name, std::set<std::string>& key_set1, std::set<std::string>& key_set2)
+{
+    std::vector<int> cur_extruder_ids, target_extruder_ids, variant_index;
+    std::vector<std::string> cur_extruder_variants, target_extruder_variants;
+
+    if (!extruder_id_name.empty()) {
+        if (this->option(extruder_id_name))
+            cur_extruder_ids = this->option<ConfigOptionInts>(extruder_id_name)->values;
+        if (new_config.option(extruder_id_name))
+            target_extruder_ids = new_config.option<ConfigOptionInts>(extruder_id_name)->values;
+    }
+    if (this->option(extruder_variant_name))
+        cur_extruder_variants = this->option<ConfigOptionStrings>(extruder_variant_name, true)->values;
+    if (new_config.option(extruder_variant_name))
+        target_extruder_variants = new_config.option<ConfigOptionStrings>(extruder_variant_name, true)->values;
+
+    int cur_variant_count = cur_extruder_variants.size();
+    int target_variant_count = target_extruder_variants.size();
+
+    variant_index.resize(cur_variant_count, -1);
+    if (target_variant_count == 0) {
+        variant_index[0] = 0;
+    }
+    else if ((cur_extruder_ids.size() > 0) && cur_variant_count != cur_extruder_ids.size()){
+        //should not happen
+        BOOST_LOG_TRIVIAL(error) << __FUNCTION__ << boost::format(" size of %1% = %2%, not equal to size of %3% = %4%")
+             %extruder_variant_name %cur_variant_count %extruder_id_name %cur_extruder_ids.size();
+    }
+    else if ((target_extruder_ids.size() > 0) && target_variant_count != target_extruder_ids.size()){
+        //should not happen
+        BOOST_LOG_TRIVIAL(error) << __FUNCTION__ << boost::format(" size of %1% = %2%, not equal to size of %3% = %4%")
+             %extruder_variant_name %target_variant_count %extruder_id_name %target_extruder_ids.size();
+    }
+    else {
+        for (int i = 0; i < cur_variant_count; i++)
+        {
+            for (int j = 0; j < target_variant_count; j++)
+            {
+                if ((cur_extruder_variants[i] == target_extruder_variants[j])
+                    &&(cur_extruder_ids.empty() || (cur_extruder_ids[i] == target_extruder_ids[j])))
+                {
+                    variant_index[i] = j;
+                    break;
+                }
+            }
+        }
+    }
+
+    const t_config_option_keys &keys = new_config.keys();
+    for (auto& opt : keys) {
+        if ((opt == extruder_id_name) || (opt == extruder_variant_name))
+            continue;
+        ConfigOption *opt_src = this->option(opt);
+        const ConfigOption *opt_target = new_config.option(opt);
+        if (opt_src && opt_target && (*opt_src != *opt_target)) {
+            BOOST_LOG_TRIVIAL(debug) << __FUNCTION__ << boost::format(" change key %1% from base_value %2% to child's value %3%")
+                    %opt %(opt_src->serialize()) %(opt_target->serialize());
+            if (opt_target->is_scalar()
+                || ((key_set1.find(opt) == key_set1.end()) && (key_set2.empty() || (key_set2.find(opt) == key_set2.end())))) {
+                //nothing to do, keep the original one
+                opt_src->set(opt_target);
+            }
+            else {
+                ConfigOptionVectorBase* opt_vec_src = static_cast<ConfigOptionVectorBase*>(opt_src);
+                const ConfigOptionVectorBase* opt_vec_dest = static_cast<const ConfigOptionVectorBase*>(opt_target);
+                int stride = 1;
+                if (key_set2.find(opt) != key_set2.end())
+                    stride = 2;
+                opt_vec_src->set_only_diff(opt_vec_dest, variant_index, stride);
+            }
+        }
+    }
+    return;
+}
+
 bool DynamicPrintConfig::is_custom_defined()
 {
     auto* is_custom_defined = dynamic_cast<const ConfigOptionStrings*>(this->option("is_custom_defined"));
diff --git a/src/libslic3r/PrintConfig.hpp b/src/libslic3r/PrintConfig.hpp
index cd3d445bb..34c8dabd4 100644
--- a/src/libslic3r/PrintConfig.hpp
+++ b/src/libslic3r/PrintConfig.hpp
@@ -502,6 +502,7 @@ public:
 
     void update_non_diff_values_to_base_config(DynamicPrintConfig& new_config, const t_config_option_keys& keys, const std::set<std::string>& different_keys, std::string extruder_id_name, std::string extruder_variant_name,
         std::set<std::string>& key_set1, std::set<std::string>& key_set2 = std::set<std::string>());
+    void update_diff_values_to_child_config(DynamicPrintConfig& new_config, std::string extruder_id_name, std::string extruder_variant_name, std::set<std::string>& key_set1, std::set<std::string>& key_set2);
 
     bool is_custom_defined();
 };
@@ -510,6 +511,7 @@ extern std::set<std::string> print_options_with_variant;
 extern std::set<std::string> filament_options_with_variant;
 extern std::set<std::string> printer_options_with_variant_1;
 extern std::set<std::string> printer_options_with_variant_2;
+extern std::set<std::string> empty_options;
 
 void handle_legacy_sla(DynamicPrintConfig &config);