diff --git a/src/slic3r/GUI/GLCanvas3D.cpp b/src/slic3r/GUI/GLCanvas3D.cpp
index 7f4b232d7..f911c2ae9 100644
--- a/src/slic3r/GUI/GLCanvas3D.cpp
+++ b/src/slic3r/GUI/GLCanvas3D.cpp
@@ -3006,6 +3006,9 @@ void GLCanvas3D::reload_scene(bool refresh_immediately, bool force_full_scene_re
             bool filament_printable = cur_plate->check_filament_printable(wxGetApp().preset_bundle->full_config(), filament_printable_error_msg);
             _set_warning_notification(EWarning::FilamentPrintableError, !filament_printable);
 
+            bool mix_pla_and_petg = cur_plate->check_mixture_of_pla_and_petg(wxGetApp().preset_bundle->full_config());
+            _set_warning_notification(EWarning::MixUsePLAAndPETG, !mix_pla_and_petg);
+
             bool model_fits = contained_min_one && !m_model->objects.empty() && !partlyOut && object_results.filaments.empty() && tpu_valid;
             post_event(Event<bool>(EVT_GLCANVAS_ENABLE_ACTION_BUTTONS, model_fits));
             ppl.get_curr_plate()->update_slice_ready_status(model_fits);
@@ -3017,6 +3020,7 @@ void GLCanvas3D::reload_scene(bool refresh_immediately, bool force_full_scene_re
             //_set_warning_notification(EWarning::SlaSupportsOutside, false);
            _set_warning_notification(EWarning::TPUPrintableError, false);
            _set_warning_notification(EWarning::FilamentPrintableError, false);
+           _set_warning_notification(EWarning::MixUsePLAAndPETG, false);
            post_event(Event<bool>(EVT_GLCANVAS_ENABLE_ACTION_BUTTONS, false));
         }
     }
@@ -10161,6 +10165,9 @@ void GLCanvas3D::_set_warning_notification(EWarning warning, bool state)
         error = ErrorType::SLICING_ERROR;
         break;
     }
+    case EWarning::MixUsePLAAndPETG:
+        text = _u8L("PLA and PETG filaments detected in the mixture. Adjust parameters according to the Wiki to ensure print quality.");
+        break;
     }
     //BBS: this may happened when exit the app, plater is null
     if (!wxGetApp().plater())
diff --git a/src/slic3r/GUI/GLCanvas3D.hpp b/src/slic3r/GUI/GLCanvas3D.hpp
index 579b5238a..bf5ffc0fb 100644
--- a/src/slic3r/GUI/GLCanvas3D.hpp
+++ b/src/slic3r/GUI/GLCanvas3D.hpp
@@ -385,7 +385,8 @@ class GLCanvas3D
         FilamentPrintableError,
         MultiExtruderPrintableError,      // after slice
         MultiExtruderHeightOutside,       // after slice
-        FilamentUnPrintableOnFirstLayer
+        FilamentUnPrintableOnFirstLayer,
+        MixUsePLAAndPETG
     };
 
     class RenderStats
diff --git a/src/slic3r/GUI/PartPlate.cpp b/src/slic3r/GUI/PartPlate.cpp
index 9e3a947d1..dce2e3fcf 100644
--- a/src/slic3r/GUI/PartPlate.cpp
+++ b/src/slic3r/GUI/PartPlate.cpp
@@ -1364,6 +1364,29 @@ bool PartPlate::check_tpu_printable_status(const DynamicPrintConfig & config, co
     return tpu_valid;
 }
 
+bool PartPlate::check_mixture_of_pla_and_petg(const DynamicPrintConfig &config)
+{
+    bool has_pla = false;
+    bool has_petg = false;
+
+    std::vector<int> used_filaments = get_extruders(true); // 1 base
+    if (!used_filaments.empty()) {
+        for (auto filament_idx : used_filaments) {
+            int                 filament_id        = filament_idx - 1;
+            std::string         filament_type      = config.option<ConfigOptionStrings>("filament_type")->values.at(filament_id);
+            if (filament_type == "PLA")
+                has_pla = true;
+            if (filament_type == "PETG")
+                has_petg = true;
+        }
+    }
+
+    if (has_pla && has_petg)
+        return false;
+
+    return true;
+}
+
 Vec3d PartPlate::estimate_wipe_tower_size(const DynamicPrintConfig & config, const double w, const double wipe_volume, int plate_extruder_size, bool use_global_objects) const
 {
 	Vec3d wipe_tower_size;
diff --git a/src/slic3r/GUI/PartPlate.hpp b/src/slic3r/GUI/PartPlate.hpp
index b8c490adb..bcb8e267a 100644
--- a/src/slic3r/GUI/PartPlate.hpp
+++ b/src/slic3r/GUI/PartPlate.hpp
@@ -316,6 +316,7 @@ public:
     int  get_physical_extruder_by_filament_id(const DynamicConfig& g_config, int idx) const;
     bool check_filament_printable(const DynamicPrintConfig & config, wxString& error_message);
     bool check_tpu_printable_status(const DynamicPrintConfig & config, const std::vector<int> &tpu_filaments);
+    bool check_mixture_of_pla_and_petg(const DynamicPrintConfig & config);
 
     /* instance related operations*/
     //judge whether instance is bound in plate or not
diff --git a/src/slic3r/GUI/Plater.cpp b/src/slic3r/GUI/Plater.cpp
index a13272cb3..c93cbe953 100644
--- a/src/slic3r/GUI/Plater.cpp
+++ b/src/slic3r/GUI/Plater.cpp
@@ -3837,7 +3837,7 @@ Plater::priv::priv(Plater *q, MainFrame *main_frame)
 		"nozzle_height", "skirt_loops", "skirt_distance",
         "brim_width", "brim_object_gap", "brim_type", "nozzle_diameter", "single_extruder_multi_material",
         "enable_prime_tower", "wipe_tower_x", "wipe_tower_y", "prime_tower_width", "prime_tower_brim_width", "prime_tower_outer_first", "prime_tower_skip_points", "prime_volume",
-        "extruder_colour", "filament_colour", "material_colour", "printable_height", "extruder_printable_height", "printer_model", "printer_technology",
+        "extruder_colour", "filament_colour", "filament_type", "material_colour", "printable_height", "extruder_printable_height", "printer_model", "printer_technology",
         // These values are necessary to construct SlicingParameters by the Canvas3D variable layer height editor.
         "layer_height", "initial_layer_print_height", "min_layer_height", "max_layer_height",
         "brim_width", "wall_loops", "wall_filament", "sparse_infill_density", "sparse_infill_filament", "top_shell_layers",
@@ -14460,7 +14460,7 @@ void Plater::on_config_change(const DynamicPrintConfig &config)
                 continue;
             }
         }
-        if (opt_key == "material_colour") {
+        if (opt_key == "material_colour" || opt_key == "filament_type") {
             update_scheduled = true; // update should be scheduled (for update 3DScene)
         }